Anti-CRAT Antibody
Catalog No : IGX-43355
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation (PMID:15099582, PMID:29395073). Responsible for the synthesis of short- and branched-chain acylcarnitines (PMID:23485643). Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates (PMID:23485643). Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates (PMID:23485643). | ||
|---|---|---|---|
| Other names | Carnitine O-acetyltransferase, Carnitine acetylase, EC 2.3.1.7, Carnitine acetyltransferase, CAT, CrAT, CRAT, CAT1 | ||
| Cellular localization | Endoplasmic Reticulum, Mitochondrion Inner Membrane, Peripheral Membrane, Peroxisome, Mitochondrion | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P43155 | ||
| Product name | Anti-CRAT Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43355 | ||
| Supplier’s Catalog No | IGX-43355 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Carnitine O-acetyltransferase protein (181-346AA) | ||
| Specificity | CRAT antibody detects endogenous level of CRAT protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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