Anti-FAM134B Antibody

Catalog No : IGX-43266
262.00€
188.00€

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Description Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PMID:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PMID:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PMID:19838196, PMID:26040720).
Other names Reticulophagy regulator 1, Reticulophagy receptor 1, RETREG1, FAM134B JK1
Cellular localization Cis-Golgi Network Membrane, Multi-Pass Membrane, Endoplasmic Reticulum Membrane
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9H6L5
Product name Anti-FAM134B Antibody
Catalog No IGX-43266
Supplier’s Catalog No IGX-43266
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA)
Specificity FAM134B antibody detects endogenous level of FAM134B protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).