Anti-LPCAT3 Antibody
Catalog No : IGX-43235
262.00€
188.00€
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| Description | Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. | ||
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| Other names | Lysophospholipid acyltransferase 5, LPLAT 5, EC 2.3.1.-, 1-acylglycerophosphocholine O-acyltransferase, EC 2.3.1.23, 1-acylglycerophosphoserine O-acyltransferase, EC 2.3.1.n6, Lysophosphatidylcholine acyltransferase, LPCAT, Lyso-PC acyltransferase, Lysophosphatidylcholine acyltransferase 3, Lyso-PC acyltransferase 3, Lysophosphatidylserine acyltransferase, LPSAT, Lyso-PS acyltransferase, Membrane-bound O-acyltransferase domain-containing protein 5, O-acyltransferase domain-containing protein 5, LPCAT3, MBOAT5 OACT5 | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Multi-Pass Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q6P1A2 | ||
| Product name | Anti-LPCAT3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43235 | ||
| Supplier’s Catalog No | IGX-43235 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Lysophospholipid acyltransferase 5 protein (306-363AA) | ||
| Specificity | LPCAT3 antibody detects endogenous level of LPCAT3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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