Anti-PPIL2 Antibody

Catalog No : IGX-43090
237.00€
175.00€

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Description Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PMID:11435423). May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance (PMID:15946952). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PMID:20676357).
Other names Peptidyl-prolyl cis-trans isomerase-like 2, PPIase, EC 2.3.2.27, EC 5.2.1.8, CYC4, Cyclophilin-60, Cyclophilin-like protein Cyp-60, Cyp60, hCyP-60, RING-type E3 ubiquitin transferase isomerase-like 2, Rotamase PPIL2, PPIL2
Cellular localization Nucleus
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q13356
Product name Anti-PPIL2 Antibody
Catalog No IGX-43090
Supplier’s Catalog No IGX-43090
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 2 protein (1-260AA)
Specificity PPIL2 antibody detects endogenous level of PPIL2 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).