Anti-EIF4E2 Antibody
Catalog No : IGX-42969
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PMID:9582349, PMID:17368478, PMID:25624349). Acts as a repressor of translation initiation (PMID:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap . | ||
|---|---|---|---|
| Other names | Eukaryotic translation initiation factor 4E type 2, eIF-4E type 2, eIF4E type 2, Eukaryotic translation initiation factor 4E homologous protein, Eukaryotic translation initiation factor 4E-like 3, eIF4E-like protein 4E-LP, mRNA cap-binding protein 4EHP, h4EHP, mRNA cap-binding protein type 3, EIF4E2, EIF4EL3 | ||
| Cellular localization | Cytosol, Eukaryotic Translation Initiation Factor 4F Complex, Mrna Cap Binding Complex | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O60573 | ||
| Product name | Anti-EIF4E2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42969 | ||
| Supplier’s Catalog No | IGX-42969 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Eukaryotic translation initiation factor 4E type 2 protein (1-240AA) | ||
| Specificity | EIF4E2 antibody detects endogenous level of EIF4E2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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