Anti-ABCC11 / ATP-binding cassette, sub-family C (CFTR/MRP), member 11 Antibody
Catalog No : IGX-42606
237.00€
175.00€
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| Description | Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PMID:12764137, PMID:15537867). Enhances the cellular extrusion of cAMP and cGMP (PMID:12764137, PMID:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E217betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PMID:15537867, PMID:25896536). Probably functions to secrete earwax (PMID:16444273, PMID:19383836). Required for the secretion of components contributing to axillary odor formation (PMID:19710689). | ||
|---|---|---|---|
| Other names | ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8, ABCC11, MRP8 | ||
| Cellular localization | Membrane, Multi-Pass Membrane, Vacuole Membrane, Cytoplasmic Vesicle Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96J66 | ||
| Product name | Anti-ABCC11 / ATP-binding cassette, sub-family C (CFTR/MRP), member 11 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42606 | ||
| Supplier’s Catalog No | IGX-42606 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human ATP-binding cassette sub-family C member 11 protein (1-170AA) | ||
| Specificity | ABCC11 antibody detects endogenous level of ABCC11 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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