Anti-LSS Antibody

Catalog No : IGX-42596
237.00€
175.00€

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Description Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (PMID:14766201, PMID:7639730, PMID:26200341). Through the production of lanosterol may regulate lens protein aggregation and increase transparency (PMID:26200341).
Other names Lanosterol synthase, EC 5.4.99.7, 2,3-epoxysqualene--lanosterol cyclase, Oxidosqualene--lanosterol cyclase, OSC, hOSC, LSS, OSC
Cellular localization Endoplasmic Reticulum Membrane, Peripheral Membrane
Research area Cardiovascular
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P48449
Product name Anti-LSS Antibody
Catalog No IGX-42596
Supplier’s Catalog No IGX-42596
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Lanosterol synthase protein (1-300AA)
Specificity LSS antibody detects endogenous level of LSS protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).