Anti-KCNH1 / Kv10.1 Antibody

Catalog No : IGX-42567
237.00€
175.00€

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Description Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel (PMID:9738473, PMID:11943152, PMID:10880439, PMID:22732247, PMID:25556795, PMID:27325704, PMID:27005320, PMID:27618660). Channel properties are modulated by subunit assembly (PMID:11943152). Mediates IK(NI) current in myoblasts (PMID:9738473). Involved in the regulation of cell proliferation and differentiation, in particular adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (PMID:23881642).
Other names Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1, EAG channel 1, h-eag, hEAG1, Voltage-gated potassium channel subunit Kv10.1, KCNH1, EAG EAG1
Cellular localization Nucleus Inner Membrane, Multi-Pass Membrane, Early Endosome Membrane, Membrane, Presynaptic Membrane, Postsynaptic Density Membrane, Dendrite, Axon, Perikaryon
Research area Neuroscience
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O95259
Product name Anti-KCNH1 / Kv10.1 Antibody
Catalog No IGX-42567
Supplier’s Catalog No IGX-42567
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Potassium voltage-gated channel subfamily H member 1 protein (840-989AA)
Specificity KCNH1 antibody detects endogenous level of KCNH1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).