Anti-HPS1 Antibody
Catalog No : IGX-42529
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 (PMID:23084991). | ||
|---|---|---|---|
| Other names | Hermansky-Pudlak syndrome 1 protein, HPS1, HPS | ||
| Cellular localization | Bloc-3 Complex, Cytosol, Lysosome, Cytoplasm Cytoplasmic Vesicle | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q92902 | ||
| Product name | Anti-HPS1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42529 | ||
| Supplier’s Catalog No | IGX-42529 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Hermansky-Pudlak syndrome 1 protein (1-324AA) | ||
| Specificity | HPS1 antibody detects endogenous level of HPS1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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