Anti-SERPIND1 Antibody

Catalog No : IGX-42494
237.00€
175.00€

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Description Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
Other names Heparin cofactor 2, Heparin cofactor II, HC-II, Protease inhibitor leuserpin-2, HLS2, Serpin D1, SERPIND1, HCF2
Cellular localization Endoplasmic Reticulum Lumen, Extracellular Exosome, Extracellular Region, Extracellular Space
Research area Cardiovascular
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P05546
Product name Anti-SERPIND1 Antibody
Catalog No IGX-42494
Supplier’s Catalog No IGX-42494
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Heparin cofactor 2 protein (20-290AA)
Specificity SERPIND1 antibody detects endogenous level of SERPIND1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).