Anti-ORC4 Antibody

Catalog No : IGX-42413
237.00€
175.00€

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Description Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Other names Origin recognition complex subunit 4, ORC4, ORC4L
Cellular localization Nucleus
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O43929
Product name Anti-ORC4 Antibody
Catalog No IGX-42413
Supplier’s Catalog No IGX-42413
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Origin recognition complex subunit 4 protein (187-436AA)
Specificity ORC4 antibody detects endogenous level of ORC4 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).