Anti-AFAP1 Antibody

Catalog No : IGX-42399
237.00€
175.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Description Can cross-link actin filaments into both network and bundle structures . May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
Other names Actin filament-associated protein 1, 110 kDa actin filament-associated protein, AFAP-110, AFAP1, AFAP
Cellular localization Cytoskeleton, Stress Fiber
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q8N556
Product name Anti-AFAP1 Antibody
Catalog No IGX-42399
Supplier’s Catalog No IGX-42399
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Actin filament-associated protein 1 protein (461-730AA)
Specificity AFAP1 antibody detects endogenous level of AFAP1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).