Anti-GAN Antibody

Catalog No : IGX-42327
237.00€
175.00€

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Description Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Other names Gigaxonin, Kelch-like protein 16, GAN, GAN1 KLHL16
Cellular localization Cytoplasm, Cytoskeleton
Research area Neuroscience
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9H2C0
Product name Anti-GAN Antibody
Catalog No IGX-42327
Supplier’s Catalog No IGX-42327
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Gigaxonin protein (1-240AA)
Specificity GAN antibody detects endogenous level of GAN protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).