Anti-SULT1E1 Antibody
Catalog No : IGX-42257
237.00€
175.00€
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| Description | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone (PMID:7779757, PMID:11884392, PMID:11006110). Is a key enzyme in estrogen homeostasis, the sulfation of estrogens leads to their inactivation. Also sulfates dehydroepiandrosterone (DHEA), pregnenolone, (24S)-hydroxycholesterol and xenobiotic compounds like ethinylestradiol, equalenin, diethyl stilbesterol and 1-naphthol at significantly lower efficiency (PMID:11006110, PMID:19589875). Does not sulfonate cortisol, testosterone and dopamine (PMID:7779757, PMID:11006110). | ||
|---|---|---|---|
| Other names | Estrogen sulfotransferase, EC 2.8.2.4, EST-1, Sulfotransferase 1E1, ST1E1, Sulfotransferase, estrogen-preferring, SULT1E1, STE | ||
| Cellular localization | Cytosol | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P49888 | ||
| Product name | Anti-SULT1E1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42257 | ||
| Supplier’s Catalog No | IGX-42257 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Estrogen sulfotransferase protein (140-294AA) | ||
| Specificity | SULT1E1 antibody detects endogenous level of SULT1E1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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