Anti-LIMK2 Antibody
Catalog No : IGX-42256
237.00€
175.00€
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| Description | Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PMID:10436159, PMID:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PMID:10436159, PMID:11018042). Involved in astral microtubule organization and mitotic spindle orientation during early stage of mitosis by mediating phosphorylation of TPPP (PMID:22328514). Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (PMID:8537403). | ||
|---|---|---|---|
| Other names | LIM domain kinase 2, LIMK-2, EC 2.7.11.1, LIMK2 | ||
| Cellular localization | Cytoskeleton, Spindle, Nucleus, Cytoplasm | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P53671 | ||
| Product name | Anti-LIMK2 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42256 | ||
| Supplier’s Catalog No | IGX-42256 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human LIM domain kinase 2 protein (1-240AA) | ||
| Specificity | LIMK2 antibody detects endogenous level of LIMK2 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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