Anti-ASCC3 Antibody
Catalog No : IGX-42229
237.00€
175.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions (PMID:22055184). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PMID:12077347). | ||
|---|---|---|---|
| Other names | Activating signal cointegrator 1 complex subunit 3, EC 3.6.4.12, ASC-1 complex subunit p200, ASC1p200, Helicase, ATP binding 1, Trip4 complex subunit p200, ASCC3, HELIC1 | ||
| Cellular localization | Nucleus, Nucleus Speckle | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8N3C0 | ||
| Product name | Anti-ASCC3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42229 | ||
| Supplier’s Catalog No | IGX-42229 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Activating signal cointegrator 1 complex subunit 3 protein (1-111AA) | ||
| Specificity | ASCC3 antibody detects endogenous level of ASCC3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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