Anti-COQ8A Antibody
Catalog No : IGX-42228
237.00€
175.00€
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| Description | Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PMID:25498144, PMID:21296186, PMID:25540914, PMID:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PMID:25498144, PMID:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (PMID:25498144, PMID:27499294). Shows an unusual selectivity for binding ADP over ATP (PMID:25498144). | ||
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| Other names | Atypical kinase COQ8A, mitochondrial, EC 2.7.-.-, Chaperone activity of bc1 complex-like, Chaperone-ABC1-like, Coenzyme Q protein 8A, aarF domain-containing protein kinase 3, COQ8A, ADCK3 CABC1 | ||
| Cellular localization | Mitochondrion, Membrane, Single-Pass Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8NI60 | ||
| Product name | Anti-COQ8A Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42228 | ||
| Supplier’s Catalog No | IGX-42228 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Atypical kinase COQ8A, mitochondrial protein (1-220AA) | ||
| Specificity | COQ8A antibody detects endogenous level of COQ8A protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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