Anti-SMYD3 Antibody

Catalog No : IGX-42219
237.00€
175.00€

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Description Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation (PMID:15235609, PMID:22419068). Also methylates 'Lys-5' of histone H4 (PMID:22419068). Plays an important role in transcriptional activation as a member of an RNA polymerase complex (PMID:15235609). Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences (PMID:15235609).
Other names Histone-lysine N-methyltransferase SMYD3, EC 2.1.1.43, SET and MYND domain-containing protein 3, Zinc finger MYND domain-containing protein 1, SMYD3, ZMYND1 ZNFN3A1
Cellular localization Cytoplasm, Nucleus
Research area Epigenetics & Nuclear Signaling
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9H7B4
Product name Anti-SMYD3 Antibody
Catalog No IGX-42219
Supplier’s Catalog No IGX-42219
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Histone-lysine N-methyltransferase SMYD3 protein (199-428AA)
Specificity SMYD3 antibody detects endogenous level of SMYD3 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).