Anti-EFNB1 Antibody
Catalog No : IGX-42105
237.00€
175.00€
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| Description | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PMID:8070404, PMID:7973638). Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells (PMID:8070404, PMID:7973638). Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PMID:8070404, PMID:7973638). Can also bind EPHB2 and EPHB3 (PMID:8070404). Binds to, and induces collapse of, commissural axons/growth cones in vitro . May play a role in constraining the orientation of longitudinally projecting axons . | ||
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| Other names | Ephrin-B1, EFL-3, ELK ligand, ELK-L, EPH-related receptor tyrosine kinase ligand 2, LERK-2, EFNB1, EFL3 EPLG2 LERK2 | ||
| Cellular localization | Membrane, Single-Pass Type I Membrane, Membrane Raft, Membrane, Nucleus | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P98172 | ||
| Product name | Anti-EFNB1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-42105 | ||
| Supplier’s Catalog No | IGX-42105 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Ephrin-B1 protein (28-237AA) | ||
| Specificity | EFNB1 antibody detects endogenous level of EFNB1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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