Anti-KCNN4 Antibody

Catalog No : IGX-42092
237.00€
175.00€

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Description Forms a voltage-independent potassium channel that is activated by intracellular calcium (PMID:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PMID:17157250, PMID:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PMID:24591580).
Other names Intermediate conductance calcium-activated potassium channel protein 4, SK4, SKCa 4, SKCa4, IKCa1, IK1, KCa3.1, KCa4, Putative Gardos channel, KCNN4, IK1 IKCA1 KCA4 SK4
Cellular localization Membrane, Multi-Pass Membrane
Research area Neuroscience
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O15554
Product name Anti-KCNN4 Antibody
Catalog No IGX-42092
Supplier’s Catalog No IGX-42092
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Intermediate conductance calcium-activated potassium channel protein 4 protein (288-427AA)
Specificity KCNN4 antibody detects endogenous level of KCNN4 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).