Anti-SGF29 Antibody
Catalog No : IGX-41701
262.00€
188.00€
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| Description | Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes (PMID:19103755, PMID:20850016, PMID:26421618, PMID:21685874, PMID:26578293). SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) (PMID:20850016, PMID:26421618, PMID:21685874, PMID:26578293). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me (PMID:20850016). Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival (PMID:23894581). | ||
|---|---|---|---|
| Other names | SAGA-associated factor 29, Coiled-coil domain-containing protein 101, SAGA complex-associated factor 29, SGF29, CCDC101 | ||
| Cellular localization | Nucleus | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96ES7 | ||
| Product name | Anti-SGF29 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41701 | ||
| Supplier’s Catalog No | IGX-41701 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human SAGA-associated factor 29 homolog protein (1-293AA) | ||
| Specificity | SGF29 antibody detects endogenous level of SGF29 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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