Anti-CLEC4C Antibody
Catalog No : IGX-41693
262.00€
188.00€
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| Description | Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PMID:11748283, PMID:21880719, PMID:25995448). Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PMID:21880719, PMID:25995448). Binds to serum IgG (PMID:25995448). Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PMID:11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PMID:11748283, PMID:21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PMID:11748283). | ||
|---|---|---|---|
| Other names | C-type lectin domain family 4 member C, Blood dendritic cell antigen 2, BDCA-2, C-type lectin superfamily member 7, Dendritic lectin, CD antigen CD303, CLEC4C, BDCA2 CLECSF11 CLECSF7 DLEC HECL | ||
| Cellular localization | Membrane, Single-Pass Type Ii Membrane | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q8WTT0 | ||
| Product name | Anti-CLEC4C Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41693 | ||
| Supplier’s Catalog No | IGX-41693 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human C-type lectin domain family 4 member C protein (45-213AA) | ||
| Specificity | CLEC4C antibody detects endogenous level of CLEC4C protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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