Anti-HLA-DMA Antibody
Catalog No : IGX-41315
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. | ||
|---|---|---|---|
| Other names | HLA class II histocompatibility antigen, DM alpha chain, MHC class II antigen DMA, Really interesting new gene 6 protein, HLA-DMA, DMA RING6 | ||
| Cellular localization | Late Endosome Membrane, Single-Pass Type I Membrane, Lysosome Membrane | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P28067 | ||
| Product name | Anti-HLA-DMA Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41315 | ||
| Supplier’s Catalog No | IGX-41315 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA) | ||
| Specificity | HLA-DMA antibody detects endogenous level of HLA-DMA protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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