Anti-HLA-DMA Antibody

Catalog No : IGX-41315
262.00€
188.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Description Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Other names HLA class II histocompatibility antigen, DM alpha chain, MHC class II antigen DMA, Really interesting new gene 6 protein, HLA-DMA, DMA RING6
Cellular localization Late Endosome Membrane, Single-Pass Type I Membrane, Lysosome Membrane
Research area Cardiovascular
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P28067
Product name Anti-HLA-DMA Antibody
Catalog No IGX-41315
Supplier’s Catalog No IGX-41315
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human HLA class II histocompatibility antigen, DM alpha chain protein (27-233AA)
Specificity HLA-DMA antibody detects endogenous level of HLA-DMA protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).