Anti-ACPP / Acid phosphatase prostate Antibody
Catalog No : IGX-41269
262.00€
188.00€
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| Description | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP which acts as a pain suppressor. Acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. | ||
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| Other names | Prostatic acid phosphatase, PAP, EC 3.1.3.2, 5'-nucleotidase, 5'-NT, EC 3.1.3.5, Ecto-5'-nucleotidase, Thiamine monophosphatase, TMPase, [Cleaved into: PAPf39], ACPP | ||
| Cellular localization | Secreted, Membrane, Single-Pass Type I Membrane, Lysosome Membrane, Single-Pass Type I Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P15309 | ||
| Product name | Anti-ACPP / Acid phosphatase prostate Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41269 | ||
| Supplier’s Catalog No | IGX-41269 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Prostatic acid phosphatase protein (38-386AA) | ||
| Specificity | ACPP antibody detects endogenous level of ACPP protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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