Anti-TNFRSF10D Antibody

Catalog No : IGX-41248
262.00€
188.00€

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Description Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PMID:9382840, it cannot but according to PMID:9430226, it can induce the NF-kappa-B pathway.
Other names Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, DcR2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL-R4, TRAIL receptor with a truncated death domain, CD antigen CD264, TNFRSF10D, DCR2 TRAILR4 TRUNDD
Cellular localization Membrane, Single-Pass Type I Membrane
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9UBN6
Product name Anti-TNFRSF10D Antibody
Catalog No IGX-41248
Supplier’s Catalog No IGX-41248
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Tumor necrosis factor receptor superfamily member 10D protein (58-208AA)
Specificity TNFRSF10D antibody detects endogenous level of TNFRSF10D protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).