Anti-PPP1R11 Antibody
Catalog No : IGX-41220
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PMID:27805901). Inhibitor of protein phosphatase 1 (PMID:9843442). | ||
|---|---|---|---|
| Other names | E3 ubiquitin-protein ligase PPP1R11, EC 2.3.2.27, Hemochromatosis candidate gene V protein, HCG V, Protein phosphatase 1 regulatory subunit 11, Protein phosphatase inhibitor 3, PPP1R11, HCGV TCTE5 | ||
| Cellular localization | Nucleus, Cytoplasm | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O60927 | ||
| Product name | Anti-PPP1R11 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41220 | ||
| Supplier’s Catalog No | IGX-41220 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human E3 ubiquitin-protein ligase PPP1R11 protein (1-126AA) | ||
| Specificity | PPP1R11 antibody detects endogenous level of PPP1R11 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved