Anti-RGS7 Antibody
Catalog No : IGX-41078
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PMID:10521509, PMID:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PMID:10521509). May play a role in synaptic vesicle exocytosis (PMID:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PMID:15897264). | ||
|---|---|---|---|
| Other names | Regulator of G-protein signaling 7, RGS7, RGS7 | ||
| Cellular localization | Membrane, Cytosol, Cytoplasm, Membrane, Peripheral Membrane, | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P49802 | ||
| Product name | Anti-RGS7 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-41078 | ||
| Supplier’s Catalog No | IGX-41078 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Regulator of G-protein signaling 7 protein (1-487AA) | ||
| Specificity | RGS7 antibody detects endogenous level of RGS7 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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