Anti-B4GAT1 / Beta-1,4-Galactosyltransferase 1 Antibody
Catalog No : IGX-40928
262.00€
188.00€
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| Description | Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan (PMID:25279699, PMID:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PMID:25279699, PMID:25279697). Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1) . | ||
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| Other names | Beta-1,4-glucuronyltransferase 1, EC 2.4.1.-, I-beta-1,3-N-acetylglucosaminyltransferase, iGnT, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, Poly-N-acetyllactosamine extension enzyme, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1, B4GAT1, B3GNT1 B3GNT6 | ||
| Cellular localization | Golgi Apparatus Membrane, Single-Pass Type Ii Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O43505 | ||
| Product name | Anti-B4GAT1 / Beta-1,4-Galactosyltransferase 1 Antibody | ||
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| Catalog No | IGX-40928 | ||
| Supplier’s Catalog No | IGX-40928 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Beta-1,4-glucuronyltransferase 1 protein (161-415AA) | ||
| Specificity | B4GAT1 antibody detects endogenous level of B4GAT1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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