Anti-CARMIL1 Antibody
Catalog No : IGX-40638
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PMID:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PMID:19846667). | ||
|---|---|---|---|
| Other names | F-actin-uncapping protein LRRC16A, CARMIL homolog, Capping protein regulator and myosin 1 linker protein 1, Capping protein, Arp2/3 and myosin-I linker homolog 1, Capping protein, Arp2/3 and myosin-I linker protein 1, Leucine-rich repeat-containing protein 16A, CARMIL1, CARMIL LRRC16 LRRC16A | ||
| Cellular localization | Membrane, Cytoskeleton, Cytoplasm, Lamellipodium | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q5VZK9 | ||
| Product name | Anti-CARMIL1 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40638 | ||
| Supplier’s Catalog No | IGX-40638 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA) | ||
| Specificity | CARMIL1 antibody detects endogenous level of CARMIL1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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