Anti-CDC23 Antibody

Catalog No : IGX-40481
262.00€
188.00€

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Description Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Other names Cell division cycle protein 23 homolog, Anaphase-promoting complex subunit 8, APC8, Cyclosome subunit 8, CDC23, ANAPC8
Cellular localization Cytosol, Anaphase-Promoting Complex, Nucleoplasm, Cell, Cytoplasm, Intracellular
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q9UJX2
Product name Anti-CDC23 Antibody
Catalog No IGX-40481
Supplier’s Catalog No IGX-40481
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IF
Recommended dilutions IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Cell division cycle protein 23 homolog protein (62-142AA)
Specificity CDC23 antibody detects endogenous level of CDC23 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).