Anti-TSHR Antibody
Catalog No : IGX-40261
262.00€
188.00€
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| Description | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PMID:11847099, PMID:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PMID:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PMID:11847099). Plays a central role in controlling thyroid cell metabolism . | ||
|---|---|---|---|
| Other names | Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, TSHR, LGR3 | ||
| Cellular localization | Membrane, Multi-Pass Membrane, Basolateral Membrane, Multi-Pass Membrane, | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P16473 | ||
| Product name | Anti-TSHR Antibody | ||
|---|---|---|---|
| Catalog No | IGX-40261 | ||
| Supplier’s Catalog No | IGX-40261 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IF | ||
| Recommended dilutions | IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Thyrotropin receptor protein (21-413AA) | ||
| Specificity | TSHR antibody detects endogenous level of TSHR protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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