UPK3A, Recombinant, Human, aa19-207, His-Tag (Uroplakin-3a, UP3a, Uroplakin III, UPIII, UPK3)
Catalog No : USB-029709
564.38€
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| Product name | UPK3A, Recombinant, Human, aa19-207, His-Tag (Uroplakin-3a, UP3a, Uroplakin III, UPIII, UPK3) | ||
|---|---|---|---|
| Catalog No | USB-029709 | ||
| Supplier’s Catalog No | 29709 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E.coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 23.1 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 2mM DTT, 20% glycerol, 150mM sodium chloride. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Description | UPK3A belongs to the uroplakin-3 family. Uroplakins (UP) are key components of the urothelium. They are transmembrane proteins that pass the lipid bilayer once (UPII, UPIIIa, and UPIIIb) or four times (UPIa and UPIb; both belonging to the "tetraspanin" family). All have large luminal/extracellular domains, but only UPIIIa and UPIIIb have significant cytoplasmic portions in their C-termini. UPK3A is a highly specific and moderately sensitive immunohistochemical marker for primary and metastatic urothelial carcinomas. Mutations in this gene may be associated with renal adysplasia. Source: Recombinant corresponding to aa19-207 from human UPK3A, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMVNLQP QLASVTFATN NPTLTTVALE KPLCMFDSKE ALTGTHEVYL YVLVDSAISR NASVQDSTNT PLGSTFLQTE GGRTGPYKAV AFDLIPCSDL PSLDAIGDVS KASQILNAYL VRVGANGTCL WDPNFQGLCN PPLSAATEYR FKYVLVNMST GLVEDQTLWS DPIRTNQLTP YSTIDTWPGR RSGG Molecular Weight: ~23.1kD (MALDI-TOF) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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