Auranofin
Catalog No : USB-002985
423.00€
0.00€
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| Product name | Auranofin | ||
|---|---|---|---|
| Catalog No | USB-002985 | ||
| Supplier’s Catalog No | 2985 | ||
| Supplier | US Biologicals | ||
| Source antigen | Synthetic | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 678.48 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | |||
| Purity | |||
| Form | White to off-white crystalline powder | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Description | Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase. Synonyms: (S)-Triphenylphosphine gold(I) 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside; 1-Thio-b-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate; 3,4,5-Triacetyloxy-6-(acetyloxymethyl) oxane-2-thiolate triethylphosphanium CAS No: 34031-32-8 Molecular Formula: C₂₀H₃₄AuO₉PS Molecular Weight: 678.48 Appearance: White to off-white crystalline powder Assay (Gold content): 28-31% Specific Optical Rotation[α]20 (c=1, CHCl): -40 to -58° Melting Point: 110-118°C Solubility: Chloroform (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months ater receipt. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. | ||
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