Recombinant Human LTK (N-GST tag)

Catalog No : IGX-RP898
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Product name Recombinant Human LTK (N-GST tag)
Catalog No IGX-RP898
Supplier’s Catalog No IGX-RP898
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 70
Storage -70°C
Other names TYK1
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description LTK is a member of the ros/insulin receptor family of tyrosine kinases. LTK express a gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain and it may encode a signal transduction subunit for one or more of the hematopoietic receptors . LTK gene produces not only the putative receptor tyrosine kinase for an unknown ligand but also multiple protein products that may have different functions . LTK causes upregulation of the PI3K pathway and possibly form a genetic component of susceptibility to abnormal proliferation of self-reactive B cells in SLE (3).