Recombinant Human IRAK2 (N-GST tag)
Catalog No : IGX-RP877
366.40€
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| Product name | Recombinant Human IRAK2 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP877 | ||
| Supplier’s Catalog No | IGX-RP877 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 103 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IRAK-2, MGC150550 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Â Interleukin-1 receptor-associated kinase 2 (IRAK2) is important downstream signaling components of Toll-like receptors (TLRs) . IRAKs were first described as signal transducers for IL-1 and later have been implicated in signal transduction of other members of the Toll/IL-1 receptor family. The interleukin-1 receptor (IL-1R) signaling pathway leads to NF?B activation in mammals. To date, four mammalian IRAKs have been identified (IRAK-1, IRAK-2, IRAK-4, and IRAK-M) . It is believed that IRAK-2 could be an additional therapeutic target for inhibiting IL-1-induced inflammation. | ||
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