Recombinant Human IKK epsilon (N-GST tag)

Catalog No : IGX-RP875
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Product name Recombinant Human IKK epsilon (N-GST tag)
Catalog No IGX-RP875
Supplier’s Catalog No IGX-RP875
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 110
Storage -70°C
Other names IKBKE, IKKE, IKKI, IKK-i, KIAA0151, MGC125294, MGC125295
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description IKK epsilon is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways that has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines . IKK-epsilon is a part of a novel PMA-inducible I-kappa-B kinase complex which play an essential role for an in triggering the host antiviral response to viral infection. IKKE plays a critical role in the IFN-inducible antiviral transcriptional response .