Recombinant Human CDC7/DBF4 (N-GST tag)

Catalog No : IGX-RP759
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Product name Recombinant Human CDC7/DBF4 (N-GST tag)
Catalog No IGX-RP759
Supplier’s Catalog No IGX-RP759
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 94
Storage -70°C
Other names CDC7: CDC7L1; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; DBF4: ASK; CHIF; DBF4A; ZDBF1
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines . CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase .