Recombinant Human CDC42BPG (DMPK2) (N-GST tag)
Catalog No : IGX-RP758
366.40€
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| Product name | Recombinant Human CDC42BPG (DMPK2) (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP758 | ||
| Supplier’s Catalog No | IGX-RP758 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 78 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | DMPK2; HSMDPKIN; KAPPA-200; MRCKG; MRCKgamma | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Serine/threonine-protein kinase MRCK?, encoded by CDC42BPG gene, acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain. | ||
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