Recombinant Human TWEAK (TNFSF12)
Catalog No : IGX-RP535
696.94€
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| Product name | Recombinant Human TWEAK (TNFSF12) | ||
|---|---|---|---|
| Catalog No | IGX-RP535 | ||
| Supplier’s Catalog No | IGX-RP535 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 17.2 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | TWEAK, Tumor necrosis factor ligand superfamily member 12, TNFSF12, DR3LG, Apo3-Ligand<br/>Recombinant Human TNF-Related Weak Inducer of Apoptosis (TNFSF12) | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | TWEAK is a TNF superfamily transmembrane protein which is expressed in many different cells and tissues, such as the heart, spleen and small intestine. Two different receptors have been identified that bind TWEAK; the Death Receptor 3 (DR3) and the TWEAK Receptor (TWEAKR). While DR3 is expressed mainly in tissues that have high concentration of lymphocytes, the mitogen-inducible TWEAKR is has been shown to be expressed in fibroblasts, hepetocellular carcinomas and endothelial cells. Recombinant human TWEAK comprises the TNF homologous (secreted region) of TWEAK. | ||
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