Recombinant Human Chemerin
Catalog No : IGX-RP529
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| Product name | Recombinant Human Chemerin | ||
|---|---|---|---|
| Catalog No | IGX-RP529 | ||
| Supplier’s Catalog No | IGX-RP529 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 16 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | RAR-responsive protein TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RARRES2 | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in PBS | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Human Chemerin, also known as Tazarotene induced Gene 2 (TIG2), is an adipokine that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1. Its other ligands include G protein-coupled receptor 1 and chemokine receptor-like 2. Chemerin is expressed in various tissues where its biologically active form is generated by proteolytic removal of C-terminal residues by circulating proteases. In human, the soluble protoform gets processed into a monomeric, heparin binding bioactive molecule that can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. | ||
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