Recombinant Human NAP-2 (PPBP) (CXCL7)

Catalog No : IGX-RP335
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Product name Recombinant Human NAP-2 (PPBP) (CXCL7)
Catalog No IGX-RP335
Supplier’s Catalog No IGX-RP335
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 8
Storage -70°C
Other names CXCL7, PBP (parent molecule), NAP2, CTAP-III (precursor), Platelet basic protein, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, SCYB7, TGB1, THBGB1<br/>Recombinant Human Neutrophil Activating Peptide-2 (PPBP)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant NAP-2 was lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5._x000D_ _x000D_
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description The chemokine neutrophil- activating peptide 2 (NAP-2) is a 70-amino acid residue polypeptide that is formed from platelet-derived precursors by proteolytic processing. Mature NAP-2 stimulates various effector functions of polymorphonuclear neutrophil granulocytes (PMN) including directed chemotactic migration, exocytosis of lysosomal enzymes and secondary granule contents, and up-regulation of adhesion receptors. NAP-2 has been assigned to a subfamily now termed alpha-chemokines. The alpha-chemokines contain four cysteine residues at highly conserved positions which enclose the core region of the molecules. The first two cysteines are separated by a single amino acid, forming a motif (CXC) that distinguishes the alpha-chemokine from the beta-chemokine subfamily, where these cysteines are in directly adjacent position.