Recombinant Human Epiregulin (EREG)
Catalog No : IGX-RP305
3508.60€
0.00€
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| Product name | Recombinant Human Epiregulin (EREG) | ||
|---|---|---|---|
| Catalog No | IGX-RP305 | ||
| Supplier’s Catalog No | IGX-RP305 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 6 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | EPR, Proepiregulin, EREG | ||
| Grade | Highly Purified | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Human Epiregulin was lyophilized from a 0.2 μm filtered solution in PBS pH 7.5. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Epiregulin acts as a local signal mediator and shows dual biological activity, stimulating the proliferation of fibroblasts, hepatocytes, smooth muscle cells, and keratinocytes while also inhibiting the growth of several tumor-derived epithelial cell lines. Epiregulin was first identified in NIH 3T3 cell conditioned medium, and is one of the seven known ligands for the epidermal growth factor receptor (EGFR). Epiregulin is synthesized as a transmembrane precursor before being proteolytically cleaved to release a 46-amino-acid active protein. Epiregulin also shows more potent bioactivity in vitro than other EGF-like growth factors | ||
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