Recombinant Human WNT1

Catalog No : IGX-RP298
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Product name Recombinant Human WNT1
Catalog No IGX-RP298
Supplier’s Catalog No IGX-RP298
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 38.5
Storage -70°C
Other names Proto-oncogene Int-1 homolog, Wnt-1<br/>Recombinant Human Proto-oncogene Wnt-1 (WNT1)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in Tris and DTT
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Wnt-1 is a secreted protein that signals through the frizzled family of seven transmembrane receptors. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the up-regulation of over fifty genes. Stabilization and resulting accumulation of the intracellular signaling protein β-catenin is an important aspect of Wnt-1 signaling. While known to play in role as a developmental protein, elevated levels of Wnt proteins have also been associated with tumorigenesis.