Recombinant Human FGF3

Catalog No : IGX-RP260
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Product name Recombinant Human FGF3
Catalog No IGX-RP260
Supplier’s Catalog No IGX-RP260
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 21.2
Storage -70°C
Other names HBGF-3, FGF3, Proto-oncogene Int-2, Heparin-binding growth factor 3
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS, DTT and EDTA
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description FGF3 belongs to the FGF family, members of which act on cells of mesodermal and neuroectodermal origin. Originally designated int2, the FGF3 gene was initially identified as a protooncogene in mice. FGF3 plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation and is required for normal ear development. Heparan sulfate glycosaminoglycans function as co-receptors to increase the affinity between FGF3 and its receptors; FGFR1 and FGFR2. Human and mouse FGF3 are known to share 88% amino acid sequence identity. Recombinant Human FGF3 is a single polypeptide of 21 kDa.