Recombinant Human Activin A (INHBA)

Catalog No : IGX-RP245
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Product name Recombinant Human Activin A (INHBA)
Catalog No IGX-RP245
Supplier’s Catalog No IGX-RP245
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 13
Storage -70°C
Other names Activin beta-A chain, Inhibin beta-A chain, Erythroid differentiation protein, INHBA, FSH releasing protein
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a concentrated protein solution containing 0.02% TFA
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Part of the TGF-β family, inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic, pituitary and gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development and bone growth depending on their subunit composition. Activin A is a disulfide linked homodimer (two beta-A chains) that binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant Human Activin A is a homodimeric, non-glycosylated protein that has a molecular weight of 26 kDa.