Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			Bone marrow tyrosine kinase, ETK, PSCTK2, PSCTK3
Grade			Highly Purified
Purity			>80% as determined by SDS-PAGE
Form			Recombinant BMX is stored in 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol at 0.1 µg/µl.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>80% as determined by SDS-PAGE
Description			Recombinant full-length human BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX is found to induce activation of the Stat signalling pathway.