Recombinant Human TGF Beta-1 (TGFB1)

Catalog No : IGX-RP237
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Product name Recombinant Human TGF Beta-1 (TGFB1)
Catalog No IGX-RP237
Supplier’s Catalog No IGX-RP237
Supplier ImuGeX
Source antigen HEK293 cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 26
Storage -70°C
Other names Transforming growth factor beta-1, TGF-beta-1, Differentiation inhibiting factor, Latency-associated peptide, LAP
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Lyophilized from 0.2 μm filtered PBS solution pH 7.4
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description TGFB1 is the prototype member of the TGF-beta super-family that includes Inhibins, Activin A, MIS (Müllerian inhibiting substance), BMP (bone morphogenetic proteins), dpp (decapentaplegic) and Vg-1. TGFB1 is the most potent known growth inhibitor for normal and transformed epithelial cells, endothelial cells, fibroblasts, neuronal cells, lymphoid cells and other hematopoietic cell types. TGF-beta inhibits the proliferation of T lymphocytes by down-regulating predominantly IL2 mediated proliferative signals and also inhibits the growth of natural killer cells. Recombinant human TGFB1 is a disulfide linked homodimer protein that migrates at approximately 26kDa under non-reducing conditions.