Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			IL-6, IL-6/26 kDa protein, B cell stimulatory factor 2, BSF-2, B cell differentiation factor, BCDF, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IFNB2, HPGF, HSF, MGI-2<br/>Recombinant Human Interleukin-6 (IL6)
Grade			Highly Purified
Purity			>95% as determined by SDS-PAGE
Form			Interleukin-6 was lyophilized from a 0.2 μm filtered PBS solution pH 7.0.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			IL-6 is a pleiotropic cytokine that participates in a wide variety of biological functions such as acute phase response, inflammation, hematopoiesis, bone metabolism and cancer. While produced mainly by stimulated monocytes, fibroblasts and endothelial cells, IL-6 is also known to be produced by macrophages, T cells, B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells and keratinocytes, upon stimulation. Unlike murine IL-6 which is inactive on human cells, both human and murine IL-6 are equally active on murine cells. The IL-6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids (designated CD126). Recombinant human IL-6 is a 21 kDa, glycosylated protein that contains two disulfide bridges.