Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			IL-2, T-cell growth factor, TCGF, INN=Aldesleukin<br/>Recombinant Human Interleukin-2 (IL2)
Grade			Highly Purified
Purity			>95% as determined by SDS-PAGE
Form			Recombinant Interleukin-2 was lyophilized from a 0.2 μm filtered concentrated (1.0 mg/mL) solution in PBS, pH 7.2.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			IL-2 is produced mainly by T cells expressing the surface antigen CD4 following cell activation by mitogens or allogen. Interleukin-2 (IL-2) has multiple, sometimes opposing, functions during an inflammatory response. It is a potent inducer of T cell proliferation. Th1 and Th2 effector T cell differentiation and provides T cells with a long-lasting competitive advantage resulting in the optimal survival and function of memory cells. In a regulatory role, IL-2 is important for the development, survival, and function of regulatory T cells, it enhances Fas- mediated activation-induced cell death, and it inhibits the development of inflammatory Th17 cells. Thus, in its dual and contrasting functions, IL-2 contributes to both the induction and the termination of inflammatory immune responses.