Recombinant Human IFNB1

Catalog No : IGX-RP200
245.06€
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Product name Recombinant Human IFNB1
Catalog No IGX-RP200
Supplier’s Catalog No IGX-RP200
Supplier ImuGeX
Source antigen CHO cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 19
Storage -70°C
Other names IFN-beta, Immune interferon, Fibroblast interferon, Leukocyte interferon, B cell interferon, Type I interferon<br/>Recombinant Human Interferon-Beta 1A (IFNB1)
Grade Highly Purified
Purity >95% as determined by SDS-PAGE
Form Recombinant IFN-b 1a was lyophilized from a 0.2 μm filtered sodium acetate solution pH 4.8.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description IFN-beta is produced mainly by fibroblasts and some epithelial cell types. The synthesis of IFN-beta can be induced by common inducers of interferons including viruses, double-stranded RNA, and micro-organisms. It is induced also by some cytokines such as TNF and IL-1. IFN-beta binds to the same receptor as IFN-alpha. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. IFN-beta increases the expression of HLA class 1 antigens and blocks the expression of HLA class 2 antigens stimulated by IFN-gamma. IFN-beta stimulates the activity of natural killer cells and hence also antibody-dependent cytotoxicity. IFN-beta shows antiproliferative activity against a number of cell lines established from solid tumors.